Page 73 of 192
Posted: Sat Jun 20, 2015 9:00 am
by Antihero
As you are browsing through the proteins in the PDB, you may notice something: most proteins are big. They contain hundreds of amino acids, even though most of the work is often done by a few amino acids on one side. Why are proteins so big? One reason that proteins are so large is that they must self-assemble inside cells. Proteins are built as floppy chains that fold all by themselves (or with a little help from chaperones) into stable, compact structures. These folded structures are stabilized by hydrogen bonds, charge-charge interactions and hydrophobic forces between the different amino acids, which all line up like pieces in a jigsaw puzzle when the protein folds. A single hydrogen bond or a few charge pairs would not be enough, but a chain of hundreds of amino acids has hundreds of interactions that together glue the protein into a stable structure.
Our cells, on the other hand, often use a zinc atom to take a short cut. By arranging two cysteines and two histidines close to each other in a chain, a protein can grab a zinc ion and fold tightly around it. In these proteins, termed zinc fingers, a short chain of 20-30 amino acids is enough to create a solid, stable structure. Zinc fingers are so useful that they are found in thousands of our proteins, and are common in all plants and animals. Surprisingly, however, bacteria do not appear to take advantage of these little structures. Many zinc fingers play essential roles in DNA recognition. Zinc fingers were originally discovered in the transcription factor TFIIIA from frog eggs, which contains nine zinc fingers in a row.
Cerberus v666 - 1 (Ankamius)
hiplop - 5 (Tere, vezokpiraka, Sonic Boom, ZZZX, Flubbernugget)
Sonic Boom - 2 (hiplop, mastin2)
Tere - 1 (Shakira Confirmed)
Not Voting: Cerberus v666, ika, Jaqen Hghar, Kari, Lying Cat, Mac, Wickedestjr
9 to lynch. Deadline is in
(expired on 2015-07-07 23:21:41)
Posted: Sat Jun 20, 2015 11:27 am
by mastin2
Probably my last post before I catch up.
I'm anticipating today being very busy, so it'd probably be best to avoid trying to get caught up today, as much as I need to.
Tomorrow's Father's Day, which I'll be celebrating with my family, so obviously I'm not going to be around then.
However, work is shifting to a Summer schedule, which means that my hours change come Monday...leaving my afternoon entirely free. I should be able to catch up then.
Posted: Sat Jun 20, 2015 12:57 pm
by Jaqen Hghar
↑ Cerberus v666 wrote: ↑ Sonic Boom wrote:I will lynch you if you say that Marquis is godfather
Stupid threats are stupid. You are right though, in my laying out of options I forgot about the weak modifier. Whoever gifted you knows the modifier on your power I would assume, so you can't lie about that...so there's no place or reason for a godfather in a game with weak cop powers.
Anyways, prior to the vote swap Shakira was by far my strongest town read, so the real point of my question is: what makes hiplop so town you'd prefer a no lynch over him?
↑ vezokpiraka wrote:vote hiplop
[b/]
Fuck you guys. You couldn't hammer this lynch yesterday, because you were bickering about bins. Bins flipped fucking town.
@Jaqen: you still think your reads are godlevel?
A man is never saying his reads are God level. In fact, a man is saying his norm is to catch 2-3 scum on D1, which is de facto saying he is wrong on some. One thing good coming from a bad Bins wagon is that a man is pretty sure all (with exception to hiplop since Bins was his counterwagon) on the Bins wagon are probtown because scum aren't wanting to be on or Bins would have been mislynched.
Posted: Sat Jun 20, 2015 1:00 pm
by Jaqen Hghar
Dont know where that Cerb quote is coming from.
Posted: Sat Jun 20, 2015 1:15 pm
by Jaqen Hghar
↑ Sonic Boom wrote:ftr:
Bins neighborized us last night
Coincidentally we got a weak cop invention last night.
That would be a game winning combination
Good thing our cop target was town! Otherwise we would be in shite
shakira confirmed town
And this one, with all his experience, is willing to risk all claiming Weak only to confirm one town. A man is calling bullshit on this.
Posted: Sat Jun 20, 2015 1:25 pm
by Jaqen Hghar
↑ Cerberus v666 wrote: ↑ Flubbernugget wrote: ↑ Lying Cat wrote:Hi Titus. Voting me is stupid. Also, sthar8 isn't really in this game. This is a Jingle game. I'll let you know if that changes.
So, there's no doc inventor in this game. I know this because we were the target of the protective invention last night, and it is in fact a commute.
Shak is now conftown unless SB is scum. I'm not super excited about either of their posting today, but I don't think we should be beating dead horses.
I'm dead tired tonight, but it seems to me like we can fairly easily jointly determine an optimal weak cop target from this point forward. No one else should target the player in question. Whoever the weak cop inventor is gives it to null reads, and they target as appointed. That way we're not losing conftown, and scum are incentivized into suboptimal nightkills. The commuter inventor is basically a doctor, and should target based on that. Does anyone see any flaws with this logic right now? I'm about to pass out, so fine toothed comb if you'd please.
I'd be more interested in copping SB tonight than lynching them tbh. Titus is great at VCA, both of them will scare town, and they're a pretty universal null/scum read.
Not 100% sure how commuter works but doesn't that create a follow the cop scenario?
Why didn't you offer a cop appoint?
I appoint Cerb
. Double checking hiplop votes before i stack mine on
I agree. Being kinda sorta conftown is awesome.
I find it unlikely a commuter could both commute and investigate someone. That's one of the big differences between the commuter granter simply being a doctor, and having an actual doctor in the game. That, and the person targeted is immune to everything, not just kills.
So, what do we have here so far?
SB gained weak cop AND got neighborized.
Lying cat received a commute.
Neither of these claims can be substantiated by anything, because bins is dead, and lying cat didn't die last night.
Jaqen: You posted in between my L-1 post and the day end. I have the same question for you I had for Shakira Confirmed. What is so town about hiplop that you preferred a no lynch over lynching him?
Tere: We'll just see what Ika says.
A man works the night shift and so isn't available at deadline yesterday or he would have grudgingly joined the hiplop wagon to prevent NL. What a man is reading on his break gave him hope for Bins still being lynched and so pushed it one last time and then returned to work.
Posted: Sat Jun 20, 2015 2:23 pm
by Shakira Confirmed
Jaqen is town as fuck. Almost conftown.
Flumy remember this pls. Will elab later.
Posted: Sat Jun 20, 2015 4:32 pm
by Sonic Boom
@1777, scum likely have a PR of their own to counteract this. For instance, we specifically got weak cop not hider. So godfather would not trigger us. Strongman kill would kill us (as it would bypass all blocking and getaway attempts).
I don't think Ika would lie about IRL. While not a trust tell he would be aware of just how bad that would puss me off that I would doubt he would risk it.
Hiplop needs to be flipped. I am thinking Mastina/Ank/Cerb/Hiplop atm.
~Titus
Posted: Sat Jun 20, 2015 4:33 pm
by Sonic Boom
Oh and for the record Bins did not give us the weak cop, so our weak cop can be substantiated.
Posted: Sat Jun 20, 2015 4:42 pm
by Jaqen Hghar
A man isn't caring who have who what. A man IS pointing out a basic principal of mafia though- if someone is neighborized, and the one who did the neighborizing is meeting Death that same night, LYNCH THE FUCK OUT OF THE REMAINING NEIGHBOR BECAUSE SOMETHING LIKELY CAME UP IN THE NEIGHBOHOOD WHICH MADE THE CAUSED THE NEIGHBORIZOR TO MEET THEIR DEMISE.
UNVOTE:
VOTE: Sonic
For Bins. Boom!
Posted: Sat Jun 20, 2015 4:46 pm
by Sonic Boom
Jaquen, Everyone knew Bins was a PR of some sort. Plus lynching us is bad as we'll die soon enough anyway. If we encounter scum, we will die. No healing can happen.
~Titus
Posted: Sat Jun 20, 2015 4:47 pm
by Sonic Boom
We just get the commute each night, and check whoever.
~Titus
Posted: Sat Jun 20, 2015 4:51 pm
by Ankamius
Titus, I'm rather disappointed that you still don't know how I operate as scum.
Posted: Sat Jun 20, 2015 4:53 pm
by Metal Sonic
↑ Jaqen Hghar wrote:A man isn't caring who have who what. A man IS pointing out a basic principal of mafia though- if someone is neighborized, and the one who did the neighborizing is meeting Death that same night, LYNCH THE FUCK OUT OF THE REMAINING NEIGHBOR BECAUSE SOMETHING LIKELY CAME UP IN THE NEIGHBOHOOD WHICH MADE THE CAUSED THE NEIGHBORIZOR TO MEET THEIR DEMISE.
UNVOTE:
VOTE: Sonic
For Bins. Boom!
still unashamed about being wrong as fuck?
Posted: Sat Jun 20, 2015 4:54 pm
by Sonic Boom
↑ Metal Sonic wrote: ↑ Jaqen Hghar wrote:A man isn't caring who have who what. A man IS pointing out a basic principal of mafia though- if someone is neighborized, and the one who did the neighborizing is meeting Death that same night, LYNCH THE FUCK OUT OF THE REMAINING NEIGHBOR BECAUSE SOMETHING LIKELY CAME UP IN THE NEIGHBOHOOD WHICH MADE THE CAUSED THE NEIGHBORIZOR TO MEET THEIR DEMISE.
UNVOTE:
VOTE: Sonic
For Bins. Boom!
still unashamed about being wrong as fuck?
ashamed of being slippy as fuck
Posted: Sat Jun 20, 2015 4:56 pm
by Jaqen Hghar
↑ Sonic Boom wrote:We just get the commute each night, and check whoever.
~Titus
So now- neighbor, weak cop, AND commuter. Check.
Posted: Sat Jun 20, 2015 4:58 pm
by Sonic Boom
read the setup 5 times over you fool
Posted: Sat Jun 20, 2015 4:58 pm
by Sonic Boom
stop being 'a man' and return to your normal playstyle if its making your IQ drop 20 points below your normal baseline
Posted: Sat Jun 20, 2015 4:59 pm
by Jaqen Hghar
↑ Sonic Boom wrote: ↑ Metal Sonic wrote: ↑ Jaqen Hghar wrote:A man isn't caring who have who what. A man IS pointing out a basic principal of mafia though- if someone is neighborized, and the one who did the neighborizing is meeting Death that same night, LYNCH THE FUCK OUT OF THE REMAINING NEIGHBOR BECAUSE SOMETHING LIKELY CAME UP IN THE NEIGHBOHOOD WHICH MADE THE CAUSED THE NEIGHBORIZOR TO MEET THEIR DEMISE.
UNVOTE:
VOTE: Sonic
For Bins. Boom!
still unashamed about being wrong as fuck?
ashamed of being slippy as fuck
You should be^^^
And a man is having no shame for being wrong on ONE.
Posted: Sat Jun 20, 2015 5:01 pm
by Jaqen Hghar
↑ Jaqen Hghar wrote: ↑ Sonic Boom wrote:We just get the commute each night, and check whoever.
~Titus
So now- neighbor, weak cop, AND commuter. Check.
And explain to a man how this one is planning to investigate while commuting. A man is finding that to be a neat trick!
Posted: Sat Jun 20, 2015 5:02 pm
by Sonic Boom
↑ Jaqen Hghar wrote: ↑ Sonic Boom wrote: ↑ Metal Sonic wrote: ↑ Jaqen Hghar wrote:A man isn't caring who have who what. A man IS pointing out a basic principal of mafia though- if someone is neighborized, and the one who did the neighborizing is meeting Death that same night, LYNCH THE FUCK OUT OF THE REMAINING NEIGHBOR BECAUSE SOMETHING LIKELY CAME UP IN THE NEIGHBOHOOD WHICH MADE THE CAUSED THE NEIGHBORIZOR TO MEET THEIR DEMISE.
UNVOTE:
VOTE: Sonic
For Bins. Boom!
still unashamed about being wrong as fuck?
ashamed of being slippy as fuck
You should be^^^
And a man is having no shame for being wrong on ONE.
oh please.
the bins one was the only one up for contention.
im pretty sure you're wrong on zx and i'm definitely sure that you're wrong on me so thats 3/3 wrong
that's usually a scumtell for someone proclaimed as a "good scumhunter" dont'cha agree?
Posted: Sat Jun 20, 2015 5:04 pm
by Sonic Boom
maybe you should consider sheeping me
Posted: Sat Jun 20, 2015 5:04 pm
by Sonic Boom
and be my assistant
Posted: Sat Jun 20, 2015 5:20 pm
by Sonic Boom
↑ Jaqen Hghar wrote: ↑ Sonic Boom wrote:We just get the commute each night, and check whoever.
~Titus
So now- neighbor, weak cop, AND commuter. Check.
Context, I was asking for the commuter, I doubt the weak cop giver would not go along with this. We did not CC the commuter claim. Seriously, knock it off Wayne.
Posted: Sat Jun 20, 2015 5:28 pm
by Jaqen Hghar
↑ Sonic Boom wrote:Jaquen, Everyone knew Bins was a PR of some sort. Plus lynching us is bad as we'll die soon enough anyway. If we encounter scum, we will die. No healing can happen. We just get the commute each night, and check whoever.
~Titus
A man
is
reading in context.